Evidence supporting the use of: Drynaria
For the health condition: Broken Bones

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Drynaria, particularly the rhizome of Drynaria fortunei, is traditionally used in Chinese medicine for the treatment of bone fractures and promoting bone healing. This use is recorded in classical texts, where it is known as "Gu Sui Bu" ("mender of shattered bones"). In recent decades, research has begun to investigate the scientific basis for these traditional claims. Preclinical studies (mainly in vitro and animal models) have demonstrated that extracts of Drynaria can stimulate osteoblast proliferation, enhance bone mineralization, and increase the expression of bone-related proteins such as alkaline phosphatase, osteocalcin, and collagen type I. Additionally, some compounds isolated from Drynaria, such as naringin, have shown osteogenic activity in laboratory studies.

However, robust clinical evidence in humans is limited. There are few high-quality randomized controlled trials, and most evidence comes from animal studies or small-scale human trials with methodological weaknesses. Thus, while there is a plausible biological mechanism and supportive preclinical data, the overall evidence level is still preliminary. Further well-designed clinical trials are needed to establish efficacy and safety for bone healing in humans. In summary, the use of Drynaria for broken bones is rooted in tradition and supported by early scientific studies, but lacks strong clinical validation at this time.

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