Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitamin B6 (pyridoxine) has traditionally been used to help alleviate symptoms associated with premenstrual syndrome (PMS), including breast swelling and tenderness (mastalgia). The rationale behind its use is based on observations from the mid-20th century that B6 plays a role in the metabolism of neurotransmitters and steroid hormones, both of which are implicated in PMS symptoms. Some early, small studies and anecdotal reports suggested that B6 supplementation might reduce symptoms such as breast discomfort, mood changes, and bloating. However, these studies were often limited by small sample sizes, lack of rigorous design, and inconsistent results. Larger, well-controlled clinical trials have not conclusively demonstrated significant benefits of B6 for breast symptoms specifically, although some modest effect on overall PMS symptoms has been noted. Most recent clinical guidelines note insufficient evidence to recommend B6 for mastalgia, but it remains a popular traditional remedy, especially among women seeking non-prescription options for PMS-related breast tenderness. Therefore, while the practice has historical and traditional roots, robust scientific validation is lacking, and the overall quality of evidence is low (rated 2/5).

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More about Breasts (swelling and tenderness)

Other ingredients used for Breasts (swelling and tenderness)

Other health conditions supported by Vitamin B6 (not specified)

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