Evidence supporting the use of: Daidzein
For the body system: Breasts

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Daidzein is an isoflavone found predominantly in soybeans and other legumes. Its use in supporting the "Breasts" body system is primarily linked to its phytoestrogenic properties, as it can weakly bind to estrogen receptors and mimic some effects of endogenous estrogen. Scientific interest has focused on daidzein for its potential role in breast health, especially regarding menopausal symptoms and possibly in breast cancer prevention or risk modulation. However, human clinical evidence remains limited and somewhat conflicting. Epidemiological studies have observed lower rates of breast cancer in populations with higher dietary isoflavone intake (such as in some Asian countries), but these findings may be influenced by many confounding factors, including overall diet and lifestyle. Some in vitro and animal studies suggest daidzein may exert both estrogenic and anti-estrogenic effects on breast tissue, but results have not been consistently replicated in humans. Current systematic reviews and meta-analyses generally conclude that while soy isoflavones like daidzein appear safe for breast tissue in moderate dietary amounts, there is insufficient high-quality clinical evidence to support the use of daidzein supplements specifically for breast health or disease prevention. Therefore, while there is a scientific rationale for its investigation and some supportive data, the overall level of evidence supporting daidzein supplementation for the "Breasts" body system is low.

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Products containing Daidzein

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