Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Jiaogulan (Gynostemma pentaphyllum) has a long history of use in traditional Chinese medicine, where it is often called the "herb of immortality." Traditionally, it has been consumed as a tea or tonic to promote general vitality, longevity, and resilience to stress. Its use in supporting the brain or cognitive function is primarily based on these traditional claims of enhancing energy and overall well-being, rather than on direct references to brain health specifically. Some traditional sources suggest it may help with alertness and mental clarity, but this is generally within the broader context of its adaptogenic properties—helping the body adapt to physical and mental stress. Modern scientific research on jiaogulan’s effects specifically on the brain is limited. A few preliminary studies in animals suggest potential neuroprotective effects, possibly due to its antioxidant and anti-inflammatory properties. However, robust clinical trials in humans evaluating its direct impact on cognitive function, memory, or other aspects of brain health are lacking. Therefore, while jiaogulan is traditionally used for overall vitality and may be implied to support the brain-body system in this context, there is insufficient scientific evidence to strongly support its use for direct brain support. Its application for brain health remains rooted in tradition rather than validated by modern research.

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