Evidence supporting the use of: Iron
For the body system: Brain

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Iron is essential for supporting the brain and nervous system, with robust scientific evidence underpinning its importance. Iron is a key cofactor in the synthesis of neurotransmitters such as dopamine, norepinephrine, and serotonin, which are crucial for mood regulation, attention, and overall cognitive function. Furthermore, iron is indispensable for proper myelination and energy metabolism within neurons. Iron deficiency, particularly during critical periods of brain development (such as infancy, childhood, and pregnancy), has been strongly linked to impaired cognitive, behavioral, and psychomotor development. Numerous studies and reviews, including those published in journals like The Lancet and American Journal of Clinical Nutrition, have demonstrated that iron supplementation in iron-deficient individuals can lead to improvements in attention, memory, and learning outcomes. Even in adults, iron deficiency can result in symptoms such as brain fog, fatigue, and impaired cognitive performance, all of which are reversible with repletion. For these reasons, iron is considered a scientifically validated ingredient to support the brain-body system, especially in populations at risk for deficiency.

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