Evidence supporting the use of: Acetyl L-carnitine
For the health condition: Body Building
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Acetyl L-carnitine (ALCAR) is a modified form of the amino acid L-carnitine, which plays a role in mitochondrial energy metabolism by facilitating the transport of fatty acids into mitochondria for oxidation. In the context of bodybuilding, ALCAR is used with the aim of enhancing fat metabolism, reducing exercise-induced fatigue, and potentially improving recovery and cognitive focus. While the theoretical basis for its use is sound—given carnitine’s role in energy production—direct scientific evidence supporting significant bodybuilding benefits is limited and mixed.
Several studies have investigated L-carnitine and its derivatives (including ALCAR) for impacts on exercise performance. Some research suggests that supplementation may reduce markers of muscle damage, decrease post-exercise soreness, and possibly improve recovery. However, the effects on muscle mass gain, strength, or direct fat loss are not robustly demonstrated. ALCAR may have additional cognitive benefits, such as reducing mental fatigue, which could indirectly benefit training intensity or adherence.
Overall, the use of acetyl L-carnitine in bodybuilding is supported by plausible mechanisms and some preliminary evidence, but well-controlled, large-scale clinical studies directly linking ALCAR supplementation to significant improvements in muscle growth, fat loss, or performance in healthy, resistance-trained individuals are lacking. Thus, the evidence level is modest, and claims should be interpreted with caution.
Other ingredients used for Body Building
7-Keto-DHEAAcetyl L-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
anchovies
ashwagandha
aspartic acid
beta-alanine
bovine
branched-chain amino acids
caffeine
capsaicinoids
Coleus forskohlii
conjugated linoleic acid (CLA)
creatine monohydrate
curcumin
gelatin
ginseng
greens blend (proprietary)
hydroxycitric acid
l-isoleucine
iron
L-cysteine
L-glutamine
L-glycine
L-leucine
L-methionine
L-ornithine
L-valine
magnesium
maltodextrin
Milk
omega-3 fatty acids
ornithine alpha-ketoglutarate
protein
Almond fruit
vitamin D
Whey protein
Zinc
wheat germ
Algae
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
4-DHEA
arginine alpha ketoglutarate
arachidonic acid
Arginine malate
Alpha glyceryl
Alpha-ketoisocaproic acid
Adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
anti-aromatase
animal protein
Beef Protein
beef
Beef liver
bovine protein
beta-lactoglobulin
ba ji tian
banana
chia seed
casein
cardarine
Citrus
capsaicin
capsiate
D-Aspartic Acid
dihydrocapsiate
deer velvet
D-Ribose
dextrose
eurycomanone
egg
Eurycoma Longifolia
ecdysteroids
Ethyl-Alpha-Guanido-Methyl-Ethanoate
ecdysterone
Egg protein
fungus
Fadogia agrestis
forskolin
glucose
hydroxymethylbutyrate
HMB hydroxymethylbutyrate
Isoleucine
ketosterones
leucine alpha-ketoglutarate
lactalbumin
lactoglobulin
lipids
Marine protein
Milk Protein
Phytoecdysteroid
Protodioscin
Phosphatidic Acid
Palatinose
propionate ester
Peptides
Rhaponticum
Synephrine
Safed musli
Ursolic Acid
Yohimbine
Zucchini
Other health conditions supported by Acetyl L-carnitine
Aging (prevention)Alzheimer's Disease
Angina
Athletic and Exercise Aids
Attention Deficit Disorder
Autism
Body Building
Burning Feet or Hands
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Chronic Obstructive Pulmonary Disorder
Circulation (poor)
Circulation (to the brain)
Concentration (poor)
Dementia
Depression
Diabetes
Down Syndrome
Endurance (lack of)
Energy (lack of)
Exercise
Fat Metabolism (poor)
Fatigue
Fibromyalgia Syndrome
Free Radical Damage
Memory and Brain Function
Multiple Sclerosis
Muscular Dystrophy
Narcolepsy
Nerve Damage
Neuralgia and Neuritis
Numbness
Paralysis
Parkinson's Disease
Peripheral Neuropathy
Post Traumatic Stress Disorder
Stress
Strokes
Testosterone (low)
Thinking (cloudy)
Tinnitus
Wasting
Weight Loss
