Evidence supporting the use of: Acetyl L-carnitine
For the health condition: Body Building
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Acetyl L-carnitine (ALCAR) is a modified form of the amino acid L-carnitine, which plays a role in mitochondrial energy metabolism by facilitating the transport of fatty acids into mitochondria for oxidation. In the context of bodybuilding, ALCAR is used with the aim of enhancing fat metabolism, reducing exercise-induced fatigue, and potentially improving recovery and cognitive focus. While the theoretical basis for its use is sound—given carnitine’s role in energy production—direct scientific evidence supporting significant bodybuilding benefits is limited and mixed.
Several studies have investigated L-carnitine and its derivatives (including ALCAR) for impacts on exercise performance. Some research suggests that supplementation may reduce markers of muscle damage, decrease post-exercise soreness, and possibly improve recovery. However, the effects on muscle mass gain, strength, or direct fat loss are not robustly demonstrated. ALCAR may have additional cognitive benefits, such as reducing mental fatigue, which could indirectly benefit training intensity or adherence.
Overall, the use of acetyl L-carnitine in bodybuilding is supported by plausible mechanisms and some preliminary evidence, but well-controlled, large-scale clinical studies directly linking ALCAR supplementation to significant improvements in muscle growth, fat loss, or performance in healthy, resistance-trained individuals are lacking. Thus, the evidence level is modest, and claims should be interpreted with caution.
Other ingredients used for Body Building
1,3,7-Trimethylpurine-2,6-dione4-DHEA
7-Keto-DHEA
Acetyl L-carnitine
adenosine 5-triphosphate disodium (ATP)
Adenosine triphosphate (ATP)
Algae
Algal protein
Almond fruit
Alpha glyceryl
Alpha hydroxyisocaproic acid
alpha-ketoglutarate (AKG)
Alpha-ketoisocaproic acid
amino acids
AMP-activated protein kinase (AMPK)
anchovies
animal protein
anti-aromatase
arachidonic acid
arginine alpha ketoglutarate
Arginine malate
ashwagandha
aspartic acid
ba ji tian
banana
beef
Beef liver
Beef Protein
beta-alanine
beta-lactoglobulin
bovine
bovine protein
branched-chain amino acids
brown rice protein
caffeine
capsaicin
capsaicinoids
capsiate
cardarine
casein
chia seed
chickpea protein
Citrus
Coleus forskohlii
conjugated linoleic acid (CLA)
creatine monohydrate
curcumin
D-Aspartic Acid
D-Ribose
deer velvet
dextrose
dihydrocapsiate
ecdysteroids
ecdysterone
egg
Egg protein
Ethyl-Alpha-Guanido-Methyl-Ethanoate
Eurycoma Longifolia
eurycomanone
Fadogia agrestis
forskolin
fungus
ginseng
glucose
greens blend (proprietary)
HMB hydroxymethylbutyrate
hydroxycitric acid
hydroxymethylbutyrate
iron
Isoleucine
ketosterones
L-cysteine
L-glutamine
L-glycine
l-isoleucine
L-leucine
L-methionine
L-ornithine
L-valine
lactalbumin
lactoglobulin
leucine alpha-ketoglutarate
lipids
magnesium
Marine protein
Milk
Milk Protein
omega-3 fatty acids
ornithine alpha-ketoglutarate
Palatinose
Peptides
Phosphatidic Acid
Phytoecdysteroid
propionate ester
protein
Protodioscin
Rhaponticum
Safed musli
Synephrine
Ursolic Acid
vitamin D
wheat germ
Whey protein
Yohimbine
Zinc
Zucchini
Other health conditions supported by Acetyl L-carnitine
Burning Feet or HandsDown Syndrome
Endurance (lack of)
Energy (lack of)
Exercise
Fatigue
Fibromyalgia Syndrome
Memory and Brain Function
Muscular Dystrophy
Narcolepsy
Nerve Damage
Neuralgia and Neuritis
Numbness
Paralysis
Peripheral Neuropathy
Aging (prevention)
Alzheimer's Disease
Cardiovascular Disease
Chronic Obstructive Pulmonary Disorder
Concentration (poor)
Dementia
Depression
Diabetes
Multiple Sclerosis
Parkinson's Disease
Strokes
Testosterone (low)
Thinking (cloudy)
Athletic and Exercise Aids
Cancer Treatment (reducing side effects)
Circulation (poor)
Circulation (to the brain)
Fat Metabolism (poor)
Free Radical Damage
Post Traumatic Stress Disorder
Stress
Tinnitus
Wasting
Weight Loss
Angina
Attention Deficit Disorder
Autism
Body Building
