Evidence supporting the use of: Trichosanthis
For the health condition: Blood Poisoning

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Trichosanthis, commonly known as Trichosanthes kirilowii or "Tian Hua Fen," has a long history of use in Traditional Chinese Medicine (TCM). In TCM, it is employed for a variety of conditions, including those believed to involve "heat" or "toxin" in the blood, which roughly corresponds to infections or inflammatory states in modern terms. The concept of "blood poisoning" in TCM is not identical to the modern biomedical concept of sepsis or bacteremia, but Trichosanthis has been used in decoctions and herbal formulas intended to "clear heat," "resolve toxins," and "reduce swelling," which may include cases of skin infections, abscesses, or fevers.

Despite its traditional use, there is limited scientific evidence supporting Trichosanthis for the treatment of blood poisoning (sepsis or systemic infection). Some in vitro and animal studies suggest that components of Trichosanthis, such as trichosanthin, possess anti-inflammatory and immunomodulatory effects, but these findings have not been translated into robust clinical trials for blood poisoning in humans. Therefore, the support for its use in this context remains primarily traditional, and the evidence level is low.

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