Evidence supporting the use of: Smilax
For the health condition: Blood Poisoning

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Smilax, commonly known as sarsaparilla, has a long-standing history in traditional medicine, particularly in Native American and European herbal practices. It was believed to act as a "blood purifier" and was commonly used for treating conditions thought to be related to "blood poisoning"—a historical term that often referred to systemic infections, sepsis, or various skin diseases. The root contains saponins and other phytochemicals, which were thought to help "cleanse" the body of toxins. In the 16th and 17th centuries, smilax was notably used in the treatment of syphilis and other infectious diseases, leading to its reputation as a remedy for blood-borne illnesses.

However, modern scientific evidence for the efficacy of smilax in treating actual blood poisoning (such as sepsis) is extremely limited. While some laboratory studies have identified anti-inflammatory and antimicrobial properties in certain smilax species, these findings have not translated into clinical evidence supporting its use for serious systemic infections. No clinical trials have demonstrated that smilax can treat or prevent sepsis or blood poisoning in humans. Its continued use for this purpose is primarily based on traditional beliefs and historical anecdote, rather than robust scientific validation. Therefore, smilax should not be relied upon for the treatment of blood poisoning, and appropriate medical care should be sought for such serious conditions.

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