Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Japanese sophora (Sophora japonica), also known as Huaihua in Traditional Chinese Medicine (TCM), has a long history of use primarily for conditions related to bleeding, such as hemorrhoids, hematuria, and hematemesis. In TCM practice, it is believed to "cool the blood" and stop bleeding, and has also been traditionally used for detoxifying the blood and treating "heat poisoning"—a concept somewhat analogous to severe infections or sepsis, referred to in lay terms as "blood poisoning." Historical texts mention its application in formulas aimed at clearing heat and toxins from the blood, which may have included what we now understand to be serious systemic infections. However, scientific evidence directly supporting the use of Japanese sophora for the treatment of sepsis or "blood poisoning" is limited. Some modern studies have examined the antibacterial and anti-inflammatory properties of certain compounds in Sophora japonica, such as flavonoids (e.g., rutin) and alkaloids, but these studies are mostly in vitro or animal models and do not specifically address clinical sepsis. Overall, while the traditional use is documented, high-quality clinical evidence is lacking, and the use for blood poisoning is not standard outside traditional medicine contexts. Always consult healthcare professionals for serious conditions like sepsis.

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