Indian tinospora (Tinospora cordifolia), also known as Guduchi or Giloy, has a long-standing history of use in traditional Indian (Ayurvedic) medicine. It is commonly employed as a "Rasayana" (rejuvenator) and is believed to boost immunity, detoxify the body, and support the body's resistance against infections. In the context of "blood poisoning"—a lay term often used for sepsis or severe systemic infection—Ayurvedic practitioners have traditionally recommended Tinospora as part of herbal formulations aimed at purifying the blood and combating infectious diseases.

The traditional rationale stems from Tinospora's reputed anti-inflammatory, immunomodulatory, and antimicrobial properties, as described in classical Ayurvedic texts. While contemporary studies have demonstrated some antibacterial and immune-boosting effects of Tinospora extracts in vitro and in animal models, robust clinical evidence in the context of sepsis or bloodstream infections is lacking. There are no well-controlled human studies specifically confirming Tinospora's efficacy for treating or supporting recovery from blood poisoning. Thus, while the traditional use is well documented, scientific validation remains weak and mostly preclinical.

In summary, Indian tinospora is traditionally used in Ayurveda to support the body's defense against systemic infections, but there is insufficient clinical evidence to support its direct use in managing blood poisoning or sepsis in modern medical practice.