Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Bitter Grass, commonly referring to various species within the genus Vernonia (such as Vernonia amygdalina), has a long-standing use in traditional medicine across parts of Africa and Asia. It is often employed as a remedy for a range of ailments, including infections and what traditional practitioners sometimes describe as "blood poisoning" (a non-specific term that may refer to sepsis, systemic infections, or blood impurities). The ethnobotanical rationale stems from Bitter Grass's perceived "cleansing" and antimicrobial properties. Several traditional systems prescribe decoctions or infusions of the leaves to treat fever, infections, and symptoms that could align with blood poisoning. However, scientific evidence specific to the use of Bitter Grass for blood poisoning (sepsis) is limited. A handful of laboratory studies indicate that extracts of Vernonia amygdalina exhibit antibacterial activity against some pathogens in vitro, and there are animal studies showing potential anti-inflammatory effects. Despite this, there is no robust clinical evidence to support its use in treating human sepsis or blood poisoning. Most support for this practice remains within the realm of traditional medicine, and the evidence rating is low due to a lack of human clinical trials or strong pharmacological validation.

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