Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Sweet clover (Melilotus officinalis) has been used in traditional medicine, particularly in Europe, for its purported blood-thinning and circulation-improving properties. Historically, sweet clover was utilized to treat conditions associated with poor blood flow, including varicose veins and mild circulatory disorders. This traditional use is primarily rooted in the presence of coumarin compounds in sweet clover, which, when metabolized, can exhibit anticoagulant effects similar to those of warfarin—a pharmaceutical derivative of coumarin. However, the naturally occurring coumarin in sweet clover does not directly act as a potent anticoagulant unless it is converted into dicoumarol, a process that can occur when the plant is spoiled or moldy.

There is limited scientific validation for the use of sweet clover as a reliable and safe means to prevent blood clots in humans. While the mechanism by which coumarin derivatives affect coagulation is well understood, the safety and efficacy of sweet clover preparations in clinical settings are not well established. Most modern use is based on tradition rather than high-quality clinical evidence, and there is a risk of toxicity, particularly with improperly processed plant material. Therefore, while sweet clover has a traditional reputation for supporting blood clot prevention, its use should be approached with caution, and it is not a substitute for standard medical anticoagulants.

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