Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Algae, particularly certain species like brown algae (Laminaria, Undaria pinnatifida), and microalgae such as Spirulina and Chlorella, have been investigated for their potential in supporting the prevention of blood clots. The primary scientific basis for this interest lies in their rich content of sulfated polysaccharides, including fucoidan and carrageenan, which have demonstrated anticoagulant and antithrombotic activities in preclinical studies. These compounds can inhibit clot formation by interfering with key steps in the coagulation cascade, somewhat analogous to the mechanism of heparin, a well-known anticoagulant. Several laboratory and animal studies have shown that extracts from algae can prolong clotting time and reduce the risk of thrombosis. For example, fucoidan has been shown to inhibit thrombin and factor Xa, two critical enzymes in clot formation, and to enhance the activity of antithrombin III. However, robust human clinical trials are still limited, and the majority of data comes from in vitro or animal models. Additionally, the potency and safety of algae-derived compounds can vary depending on the species and extraction methods. In summary, while there is promising preclinical and some early clinical evidence suggesting that algae-derived compounds may help prevent blood clots, more research in humans is needed to fully establish efficacy and safety, justifying a moderate evidence rating.

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Nature's Sunshine Super Algae