Evidence supporting the use of: Quercetin
For the health condition: Bladder (ulcerated)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Quercetin is a flavonoid found in many fruits and vegetables and has been studied for its anti-inflammatory and antioxidant properties. Its use in supporting or treating ulcerated bladder conditions, particularly interstitial cystitis/bladder pain syndrome (IC/BPS), is primarily based on scientific research. Several clinical trials and preclinical studies have explored its potential benefits for this condition. For example, a double-blind, placebo-controlled trial published in 2002 in the Journal of Urology showed that oral quercetin supplementation led to significant symptom improvement in patients with interstitial cystitis. The proposed mechanism involves quercetin's ability to stabilize mast cells, reduce histamine release, and decrease inflammation in the bladder wall, which may alleviate pain and urinary symptoms.

Despite these findings, the body of evidence is still relatively limited, with small sample sizes and a need for larger, more rigorous randomized controlled trials to confirm efficacy and safety. There are no well-established guidelines recommending quercetin as a first-line therapy, but it is sometimes used as an adjunct or alternative therapy based on the available data. Traditional use of quercetin specifically for ulcerated bladder or IC/BPS is not well documented; its application in this context is largely a result of recent scientific investigation. Nevertheless, quercetin is considered a promising option for symptom relief in some patients with bladder pain syndromes, though more research is needed to fully validate its therapeutic role.

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Other ingredients used for Bladder (ulcerated)

marshmallow
quercetin
slippery elm bark