Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Probiotics have been investigated as a supportive therapy for bladder infections (urinary tract infections, or UTIs), particularly in women who experience recurrent infections. The rationale is based on the idea that beneficial bacteria, mainly Lactobacillus species, can help maintain a healthy balance of the vaginal and urinary microbiota, thereby inhibiting the growth of uropathogens such as Escherichia coli. Several small clinical trials and systematic reviews have explored the effectiveness of oral and intravaginal probiotics in reducing the recurrence of UTIs. Some studies show a modest reduction in UTI recurrence, particularly with Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14. However, the evidence is mixed, with other studies showing little to no benefit compared to placebo or standard antibiotic prophylaxis. Guidelines from organizations such as the Infectious Diseases Society of America (IDSA) do not currently recommend probiotics as a primary or sole therapy for bladder infections, citing insufficient high-quality evidence. Nonetheless, probiotics are generally considered safe and may be used as adjunctive support, especially for patients seeking non-antibiotic preventive strategies. Overall, while there is a plausible scientific rationale and some supportive evidence, more rigorous studies are needed to confirm efficacy and determine optimal strains and dosages.

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