Evidence supporting the use of: Lactobacillus salivarius
For the health condition: Bladder Infection

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus salivarius is a probiotic bacterium that has been explored for its potential benefits in urinary tract health, including the prevention and management of bladder infections (urinary tract infections, UTIs). The scientific evidence supporting its use is limited but growing, with most studies focusing on the broader category of Lactobacillus species rather than L. salivarius specifically. The rationale for using Lactobacillus probiotics is based on their ability to restore and maintain the natural microbiota of the urogenital tract, thereby inhibiting the growth of pathogenic bacteria such as Escherichia coli, which are commonly responsible for UTIs.

L. salivarius has been shown in laboratory studies to produce antimicrobial substances (such as lactic acid and bacteriocins) that can create an unfavorable environment for pathogens. Some small clinical studies and in vitro experiments suggest that certain strains of Lactobacillus, including L. salivarius, may adhere to urogenital epithelial cells and competitively exclude uropathogens. However, the bulk of clinical research has been conducted with other species, such as L. rhamnosus and L. crispatus. Evidence specifically for L. salivarius is sparse and mostly preclinical.

In summary, while there is a scientific rationale and some preliminary evidence for the use of L. salivarius in supporting bladder health and potentially preventing infection, robust clinical data are lacking. The overall evidence rating is therefore low (2/5), and more high-quality human trials are needed to clearly establish efficacy.

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