Evidence supporting the use of: Lactobacillus acidophilus
For the health condition: Bladder Infection

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus acidophilus is a probiotic bacterium commonly found in the human gut and vaginal microbiota. Its use in supporting or treating bladder infections (urinary tract infections, UTIs) is based on its potential ability to restore and maintain a healthy balance of beneficial bacteria in the genitourinary tract. Scientific evidence for its use is modest but growing. Some clinical studies and reviews suggest that supplementation with L. acidophilus and related lactobacilli may help reduce the recurrence of UTIs, especially in women with a history of recurrent infections. The proposed mechanism involves the production of lactic acid and other substances that lower vaginal pH and inhibit the growth of uropathogens like Escherichia coli. Additionally, lactobacilli may adhere to urothelial and vaginal epithelial cells, thereby blocking the attachment of pathogenic bacteria.

However, the quality of evidence is variable. Several randomized controlled trials using oral or vaginal lactobacillus preparations show a trend toward reduced UTI recurrence, but results are not consistently statistically significant, and studies often involve small sample sizes or mixed strains. Systematic reviews, such as those by Cochrane, generally conclude that while there is some promise, more robust research is needed before probiotics can be recommended as standard therapy for bladder infections.

In summary, Lactobacillus acidophilus has a scientific rationale for use in preventing recurrent bladder infections, but current evidence is moderate (rating: 2/5). It should not replace antibiotics for active infections but may have a role in prevention, particularly in those seeking alternatives to long-term antibiotic use.

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