Evidence supporting the use of: Lactiplantibacillus plantarum
For the health condition: Bladder Infection

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactiplantibacillus plantarum (formerly Lactobacillus plantarum) has been investigated as a probiotic with potential benefits for urinary tract health, including the prevention and adjunctive treatment of bladder infections (urinary tract infections, UTIs). The scientific evidence supporting its use is modest but growing. Several in vitro and animal studies have demonstrated that L. plantarum can inhibit the growth of uropathogenic bacteria such as Escherichia coli by producing antimicrobial substances (bacteriocins), acidifying the local environment, and competing for adhesion sites on the mucosal lining.

Some small clinical trials and pilot studies in women with recurrent UTIs have used multi-strain probiotic formulations containing L. plantarum (often in combination with other lactobacilli) and reported reduced recurrence rates and improvements in urinary symptoms. However, these studies often lack large sample sizes or placebo controls, and the effects specifically attributable to L. plantarum (versus other strains) remain unclear. Systematic reviews and meta-analyses conclude that while the use of oral or vaginal probiotics may be modestly effective in reducing UTI recurrence, the quality of evidence is low to moderate and strain-specific data are limited.

Overall, there is emerging scientific rationale and preliminary clinical evidence for the use of L. plantarum to support bladder health, but further high-quality studies are needed to establish its efficacy for treating or preventing bladder infections.

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