Evidence supporting the use of: Goldenseal
For the body system: Bladder

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Goldenseal (Hydrastis canadensis) has a long history of use in traditional herbal medicine, especially among Native American tribes and later in Western herbalism. It has been used to support urinary tract and bladder health, primarily due to its purported antimicrobial and anti-inflammatory properties. The root contains alkaloids such as berberine, hydrastine, and canadine, which are believed to have some antibacterial effects. Historically, goldenseal teas, tinctures, or powders were used to help alleviate symptoms of urinary tract infections (UTIs) and bladder inflammation.

However, the scientific evidence supporting goldenseal's effectiveness for bladder health is limited. While berberine, one of its main active compounds, has demonstrated antimicrobial activity in vitro, there is little direct clinical research confirming goldenseal’s efficacy in treating or preventing bladder infections or other urinary tract conditions in humans. Most human studies are small, not specific to bladder health, or focus on berberine extracted from other sources. Overall, goldenseal’s use for bladder support is primarily justified by historical and traditional practices rather than robust scientific validation.

In summary, goldenseal’s reputation as a bladder support herb is rooted in traditional use, with only modest evidence from laboratory studies and insufficient clinical trials to strongly support its effectiveness for this body system.

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