Evidence supporting the use of: DL-Methionine
For the body system: Bladder

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

DL-Methionine is an amino acid derivative commonly used in veterinary medicine, especially for companion animals such as cats and dogs. Its primary application related to the bladder body system is to acidify urine. By lowering urinary pH, DL-Methionine can help reduce the formation of certain types of urinary crystals and stones, particularly struvite (magnesium ammonium phosphate) uroliths, which are more likely to form in alkaline urine. This effect is well-documented in veterinary texts and clinical research, making its use scientifically justified for urinary health support in animals.

Several studies and reviews, including those published in journals such as the Journal of the American Veterinary Medical Association, have noted the efficacy of DL-Methionine in preventing recurrent struvite stone formation by maintaining a more acidic urine environment. However, its use should be carefully monitored, as excessive acidification can predispose animals to other types of stones (e.g., calcium oxalate) or metabolic complications. Evidence in human medicine is less robust, and its use for bladder health is not commonly recommended in humans outside of specific metabolic disorders.

In summary, there is moderate scientific evidence supporting the use of DL-Methionine for urinary acidification and bladder health in animals, particularly in the prevention of struvite urolithiasis. Its use should be supervised by a veterinarian to avoid potential side effects or complications.

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