Evidence supporting the use of: Lycopene
For the health condition: Benign Prostate Hyperplasia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lycopene, a carotenoid found primarily in tomatoes and other red fruits, has been studied for its potential role in supporting prostate health, including in cases of Benign Prostatic Hyperplasia (BPH). Several observational studies have suggested that higher dietary intake of lycopene is associated with a lower risk of prostate enlargement and improved urinary symptoms. The proposed mechanisms for lycopene’s effect include its antioxidant properties, modulation of growth factors, and anti-inflammatory effects, which may help reduce prostate gland proliferation and oxidative stress associated with BPH.

Despite these theoretical benefits, clinical evidence supporting lycopene’s efficacy specifically for BPH is limited and mixed. A few small randomized controlled trials (RCTs) have reported improvements in International Prostate Symptom Score (IPSS) and reductions in prostate-specific antigen (PSA) levels after lycopene supplementation. However, these studies are often limited by small sample sizes, short duration, and lack of standardized dosages. Systematic reviews and meta-analyses highlight the need for larger, well-designed clinical trials before lycopene can be firmly recommended as a treatment for BPH.

In summary, while there is a scientific rationale and some preliminary evidence for the use of lycopene in BPH, the overall strength of evidence is modest (rated 2/5). Lycopene may be considered as an adjunct for prostate health, but it should not replace established medical therapies for BPH.

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