Evidence supporting the use of: Curcumin
For the health condition: Benign Prostate Hyperplasia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Curcumin, the active component of turmeric (Curcuma longa), has been investigated for its potential benefits in managing Benign Prostatic Hyperplasia (BPH), primarily due to its anti-inflammatory and antioxidant properties. Several preclinical studies and a few small clinical trials suggest that curcumin may help alleviate symptoms associated with BPH. The proposed mechanisms include the inhibition of inflammatory pathways such as NF-κB signaling, reduction of oxidative stress, and potential modulation of androgen receptor activity, all of which are implicated in the development and progression of BPH.

A handful of clinical studies have explored curcumin’s effect on lower urinary tract symptoms (LUTS) in men with BPH. For instance, a randomized, double-blind, placebo-controlled trial published in 2019 showed that men with BPH who received curcumin supplementation experienced modest improvements in urinary symptoms and prostate volume compared to placebo. However, these studies often have limitations such as small sample sizes, short durations, and lack of long-term safety data.

While the scientific rationale is plausible and some evidence supports curcumin’s use as an adjunct therapy for BPH, the quality and quantity of clinical data are limited. Thus, curcumin cannot yet be recommended as a primary treatment for BPH, but it may be considered as a supportive option under medical supervision, pending further research.

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