Evidence supporting the use of: Cistanche
For the health condition: Benign Prostate Hyperplasia

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Cistanche (Cistanche deserticola and related species) is primarily used in Traditional Chinese Medicine (TCM) and other East Asian medical systems as a tonic herb. Its traditional indications include support for kidney function, male vitality, and as a general anti-aging remedy. In the context of Benign Prostate Hyperplasia (BPH), cistanche's use is not based on direct historical records specifically targeting prostate enlargement. Instead, its reputation as a "kidney yang" tonic — with "kidney" often conceptually linked to urogenital health in TCM — has led to its inclusion in some herbal formulas for male urinary and reproductive issues. There is limited preclinical research suggesting possible anti-inflammatory and androgen-modulating properties of cistanche, which could theoretically benefit prostate health, but robust clinical trials are lacking.

No high-quality human studies have confirmed cistanche’s efficacy for BPH. The available evidence consists largely of animal studies and in vitro experiments, which show some promise in terms of anti-inflammatory and antioxidant effects, but do not directly address BPH mechanisms or symptom improvement in humans. Therefore, the use of cistanche for BPH is justified more by tradition and broad herbal theory rather than scientific validation. Its evidence rating stands at 2 out of 5, reflecting suggestive but not convincing preclinical findings and an absence of direct clinical data.

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