Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Chrysophanics, referring to compounds containing chrysophanic acid (also known as chrysophanol), are anthraquinone derivatives found in certain plants like rhubarb (Rheum species) and cascara. Their historical use in traditional medicine, particularly in Ayurveda and Unani systems, has been primarily for skin conditions, constipation, and some inflammatory disorders. In the context of bedwetting (nocturnal enuresis), there is limited reference in traditional texts suggesting their use, often as part of broader polyherbal formulations aimed at modulating urinary function. However, these references are not widespread and lack detailed documentation or specific monographs outlining chrysophanics as a primary treatment for enuresis. Scientifically, there is no robust evidence or clinical research supporting the efficacy of chrysophanic acid or its derivatives in treating bedwetting. The mechanisms by which chrysophanics might influence urinary control are not established, and most pharmacological studies focus on their laxative and antimicrobial properties rather than effects on the urinary system. Therefore, while there may be scattered traditional mentions, the overall evidence—both traditional and scientific—is weak. Modern guidelines for the management of bedwetting do not recognize chrysophanics as a treatment option.

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