Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Phosphatidylserine (PS) is a phospholipid that plays a critical role in cell membrane function, particularly in the brain. Its use as a supplement to support cognitive function and attention-related disorders, including Attention Deficit Disorder (ADD) and Attention Deficit Hyperactivity Disorder (ADHD), is primarily rooted in emerging scientific evidence rather than historical or traditional practices. A limited number of clinical studies—mostly small-scale and preliminary—have investigated the potential benefits of PS in children with ADHD. Some of these studies have reported modest improvements in attention, hyperactivity, and impulse control, especially when PS is administered in combination with other nutrients like omega-3 fatty acids. For example, a 2012 double-blind, placebo-controlled study in Japan found that children with ADHD who took PS for two months showed improvements in ADHD symptoms compared to placebo. However, these studies are generally characterized by small sample sizes, short durations, and methodological limitations, making it difficult to draw firm conclusions about efficacy.

Currently, no major medical or psychiatric guidelines recommend phosphatidylserine as a primary treatment for ADD/ADHD. The overall quality and quantity of evidence is low to moderate, suggesting that while there is some scientific validation for its use, it is not robust or definitive. More large-scale, well-designed clinical trials are necessary to confirm whether PS supplementation offers meaningful benefits for individuals with ADD/ADHD.

More about phosphatidylserine
More about Attention Deficit Disorder

Other ingredients used for Attention Deficit Disorder

Other health conditions supported by phosphatidylserine

Products containing phosphatidylserine