Evidence supporting the use of: Iron
For the health condition: Attention Deficit Disorder

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Iron is used in the support and management of Attention Deficit Disorder (ADD/ADHD) based on scientific evidence linking iron deficiency to symptoms of inattention and hyperactivity. Several studies have found that children with ADHD often have lower serum ferritin (a marker of iron stores) compared to non-ADHD controls. Iron is a crucial cofactor in the synthesis of dopamine, a neurotransmitter involved in attention and executive function, both of which are disrupted in ADHD. Some clinical trials have investigated whether iron supplementation can improve ADHD symptoms, particularly in children with documented low ferritin levels. Results have shown modest improvements in attention and hyperactivity scores when iron-deficient individuals are supplemented with iron, though the effect is generally moderate and not as robust as with standard stimulant medications.

It is important to note that iron supplementation is not recommended for all individuals with ADHD, but specifically for those who have confirmed low iron stores. Excess iron can be harmful, so indiscriminate supplementation is discouraged. Major guidelines suggest checking ferritin levels in children with ADHD who are not responding to first-line treatments, or who have symptoms suggestive of iron deficiency. In summary, the use of iron in ADHD is scientifically justified, particularly in iron-deficient patients, but its effect is moderate and targeted rather than universal.

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