Evidence supporting the use of: Amino acids
For the health condition: Attention Deficit Disorder

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Amino acids have been investigated for their potential role in supporting or treating Attention Deficit Disorder (ADD/ADHD) primarily due to their involvement as precursors to neurotransmitters such as dopamine, norepinephrine, and serotonin, which are implicated in attention and behavioral regulation. Some clinical studies and case reports suggest that supplementation with specific amino acids—such as tyrosine (a precursor to dopamine) and tryptophan (a precursor to serotonin)—may have modest benefits in improving attention or reducing hyperactivity in individuals with ADD/ADHD. However, the overall body of evidence is limited, with many studies being small, uncontrolled, or methodologically weak. Systematic reviews and meta-analyses generally conclude that, while the rationale for amino acid supplementation is biologically plausible, robust clinical evidence for efficacy is lacking. The American Academy of Pediatrics and other major organizations do not currently endorse amino acid supplements as a primary or standard therapy for ADD/ADHD. In summary, while there is some scientific interest and preliminary data suggesting possible benefits, the evidence is not strong or consistent enough to recommend amino acids as a validated treatment for ADD/ADHD. More rigorous, large-scale clinical trials are needed to clarify their role.

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