Evidence supporting the use of: Ecdysterone
For the health condition: Athletic and Exercise Aids
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Ecdysterone, a naturally occurring ecdysteroid found in plants like spinach and in some insects, has gained attention as a potential performance-enhancing supplement for athletes. Its use is primarily justified by emerging scientific evidence, rather than longstanding traditional use in this context. Several recent studies have indicated that ecdysterone supplementation may have anabolic effects, promoting increases in muscle mass and strength. For example, a notable 2019 randomized controlled trial published in Archives of Toxicology found that resistance-trained men who consumed ecdysterone for ten weeks gained significantly more muscle mass and strength than those taking a placebo. The proposed mechanism involves the activation of the estrogen receptor beta, which may stimulate protein synthesis without the androgenic side effects associated with anabolic steroids.
However, while these findings are promising, the overall body of research is still limited, with relatively few human trials and some inconsistencies in dosages and study designs. Additionally, the long-term safety profile of ecdysterone supplementation has not been fully established. Despite its inclusion on the World Anti-Doping Agency’s (WADA) monitoring list, it is not currently banned, but ongoing research could influence its regulatory status. In summary, ecdysterone is supported by a growing but still moderate level of scientific evidence (rated 3 out of 5) for its use as an exercise and athletic aid, but further large-scale, long-term studies are required to confirm its efficacy and safety.
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7-Keto-DHEAAcetyl L-carnitine
adenosine 5-triphosphate disodium (ATP)
Alpha D-ribofuranose
alpha-ketoglutarate (AKG)
amino acids
ashwagandha
astaxanthin
bacillus subtilis
beet
beta-alanine
black tea
bovine
branched-chain amino acids
caffeine
capsaicinoids
coenzyme Q10 (CoQ10)
collagen
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
curcumin
eleuthero
ginseng
green tea
guarana
guayusa
l-isoleucine
L-alanine
L-alanyl-L-glutamine
L-arginine
l-carnitine
L-citrulline
L-glutamine
L-glycine
L-leucine
L-ornithine
L-taurine
l-tyrosine
L-valine
maca
magnesium
maltodextrin
Muira puama
Acetyl-L-Tyrosine
omega-3 fatty acids
ornithine alpha-ketoglutarate
Peppermint
protein
pyridoxal-5-phosphate (P-5-P)
Rhodiola
black ginger
spirulina
Tongkat ali
tribulus
vitamin C
Watermelon
Whey protein
suma
jiaogulan
capsicum
bee pollen
cistanche
electrolytes blend (proprietary)
Yerba mate
Algae
cocoa
brown rice protein
sea salt
1,3,7-Trimethylpurine-2,6-dione
arginine alpha ketoglutarate
antler
arginine creatine
Arginine nitrate
arachidonic acid
Arginine malate
Arginine aspartate
Alpha glyceryl
Alpha-ketoisocaproic acid
Agmatine
Adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Arginine silicate
bicarbonate
Beef Protein
bovine protein
Bulbine natalensis
ba ji tian
BCAA
Camellia sinensis
coconut
casein
cardarine
capsinoids
citrate malate
capsiate
creatine
D-Aspartic Acid
dihydrocapsiate
deer velvet
D-Ribose
Ephedra
eurycomanone
elk antler
Eurycoma Longifolia
ecdysteroids
Ethyl-Alpha-Guanido-Methyl-Ethanoate
ecdysterone
ephedrine
Fadogia agrestis
guanidinoacetic acid
Ginsenosides
Glutamine
GMS-ribose
glucose
Glycocyamine
Guaranine
Glycerol
Higenamine
hydroxymethylbutyrate
HMB hydroxymethylbutyrate
horny goat weed
isomaltulose
Isoleucine
kola nut
ketone salts
lactalbumin
Laxogenin
macamides
maral root
Mineral ascorbate
Milk Protein
Methylxanthine
Methylliberine
Mate
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macaenes
Nitrous Malate (TM) Diarginine Malate
Ornithine
Phosphocreatine
pyrroloquinoline quinone
paraxanthine
Phytoecdysteroid
pyruvate
Phosphatidic Acid
Piper nigrum
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Peptides
Quinoa Protein
Rhaponticum
ribose
robusta coffee
Synephrine
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salt
Sida cordifolia
Theobromine
Trichilia catigua
Turkesterone
Trichopus zeylanicus
Theacrine
Teacrine
Tribulus Terrestris
Valine alpha-hydroxyisocaproate
Xanthine
Yohimbine
Other health conditions supported by ecdysterone
Athletic and Exercise AidsBody Building
Endurance (lack of)
Energy (lack of)
Muscle Tone (lack of)