Evidence supporting the use of: 1,3,7-Trimethylpurine-2,6-dione
For the health condition: Athletic and Exercise Aids
Synopsis
Source of validity: Scientific
Rating (out of 5): 5
1,3,7-Trimethylpurine-2,6-dione is the chemical name for caffeine. Caffeine is one of the most well-researched and widely used ergogenic (performance-enhancing) aids in sports and exercise. Numerous studies have demonstrated that caffeine can enhance physical performance, particularly in endurance events, by reducing perceived exertion, increasing alertness, and improving reaction time. The mechanism is thought to involve antagonism of adenosine receptors, leading to increased central nervous system stimulation and greater release of neurotransmitters such as dopamine and norepinephrine.
Meta-analyses and systematic reviews, such as those published in the Journal of the International Society of Sports Nutrition and Sports Medicine, have consistently found that moderate doses of caffeine (3–6 mg/kg body weight) can improve endurance, high-intensity exercise, and strength/power performance. The International Olympic Committee and other sports governing bodies recognize caffeine as an effective, legal ergogenic aid when used appropriately. Its effects are well-documented in both trained athletes and recreational exercisers.
In summary, the use of caffeine (1,3,7-Trimethylpurine-2,6-dione) as an athletic and exercise aid is strongly supported by a large body of scientific evidence, with consistent findings across multiple types of exercise and populations.
More about 1,3,7-Trimethylpurine-2,6-dione
More about Athletic and Exercise Aids
Other ingredients used for Athletic and Exercise Aids
7-Keto-DHEAacetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha d-ribofuranose
alpha-ketoglutarate (AKG)
amino acids
ashwagandha
astaxanthin
bacillus subtilis
beet
beta-alanine
black tea
bovine
branched-chain amino acids
caffeine
capsaicinoids
coenzyme Q10 (CoQ10)
collagen
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
curcumin
eleuthero
ginseng
green tea
guarana
guayusa
l-isoleucine
l-alanine
l-alanyl-l-glutamine
l-arginine
l-carnitine
l-citrulline
l-glutamine
l-glycine
l-leucine
l-ornithine
l-taurine
l-tyrosine
l-valine
maca
magnesium
maltodextrin
muira puama
Acetyl-L-Tyrosine
omega-3 fatty acids
ornithine alpha-ketoglutarate
peppermint oil
protein
pyridoxal-5-phosphate (P-5-P)
rhodiola
black ginger
spirulina
tongkat ali
tribulus
vitamin C
watermelon
whey protein
suma
jiaogulan
capsicum
bee pollen
cistanche
electrolytes blend (proprietary)
yerba mate
algae
cocoa
brown rice protein
sea salt
1,3,7-Trimethylpurine-2,6-dione
2, 17a-dimethyl-17b-hydroxy-5a-androst-2-ene
Arginine Alpha Ketoglutarate
Antler
Arginine Creatine
Arginine nitrate
Arachidonic Acid
Arginine malate
Arginine aspartate
Alpha glyceryl
Alpha-ketoisocaproic acid
Agmatine
adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Arginine silicate
Bicarbonate
Beef Protein
Bovine Protein
Bulbine natalensis
Ba Ji Tian
BCAA
Camellia sinensis
Coconut
Casein
Cardarine
Capsinoids
Citrate malate
Capsiate
Creatine
D-Aspartic Acid
Dihydrocapsiate
Deer Velvet
D-Ribose
Ephedra
Elk antler
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Ephedrine
Isoleucine
Ketone Salts
Milk Protein
Quinoa Protein
salt
yohimbine
Other health conditions supported by 1,3,7-Trimethylpurine-2,6-dione
AsthmaAthletic and Exercise Aids
Attention Deficit Disorder
Body Building
Bronchitis
Circulation (to the brain)
Concentration (poor)
Energy (lack of)
Exercise
Fatigue
Headache (general)
Memory and Brain Function
Migraine
Narcolepsy
Parkinson's Disease
Thinking (cloudy)
Weight Loss
Worry