Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Garlic (Allium sativum) has been traditionally used in various cultures for its antimicrobial properties, but its application in treating athlete's foot (tinea pedis) is also supported by scientific studies. The primary active compound in garlic, ajoene, has demonstrated broad-spectrum antifungal activity. A double-blind, randomized clinical trial published in the Journal of the American Academy of Dermatology (2000) evaluated topical 0.6% ajoene cream in patients with tinea pedis and found cure rates comparable to standard antifungal medications like terbinafine, with minimal adverse effects. Other in vitro studies confirm that garlic extracts inhibit the growth of dermatophytes, the fungi responsible for athlete’s foot. The mechanism is believed to involve disruption of fungal cell membranes and inhibition of fungal replication. While further large-scale clinical trials would strengthen the evidence base, the existing research suggests that garlic, especially in the form of standardized topical preparations containing ajoene, can be a scientifically validated alternative or adjunct to conventional antifungal therapy for athlete's foot. However, raw garlic may cause skin irritation or allergic reactions in some individuals, so medical supervision is recommended when considering its use.

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