Arisaema species, commonly known as "Jack-in-the-pulpit" or "cobra lily," have a long history of use in traditional Chinese medicine (TCM) and other Asian medical systems. In TCM, processed forms of Arisaema tubers (after detoxification) are used for conditions described as "phlegm removal," swelling, and occasionally for joint pain or arthritic conditions. The basis for use in arthritis is tied to its traditional classification as a remedy for "wind-dampness," a TCM concept believed to cause joint pain and inflammation. However, there is a lack of modern scientific studies or clinical trials validating the efficacy or safety of Arisaema species for arthritis. Most available research on Arisaema focuses on its toxicity (primarily due to calcium oxalate crystals) and its need for careful processing before medicinal use. No high-quality human or animal studies directly support its use for arthritis by modern medical standards. Thus, the use of Arisaema for arthritis is justified by tradition rather than scientific validation, and the evidence supporting its effectiveness in this context is weak.