Evidence supporting the use of: Vitamin B3 (unspecified)
For the health condition: Arteriosclerosis

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B3, also known as niacin, has been studied for its role in supporting cardiovascular health, including conditions like arteriosclerosis (hardening and narrowing of the arteries). There is scientific evidence that niacin can improve lipid profiles by raising high-density lipoprotein (HDL) cholesterol and lowering low-density lipoprotein (LDL) cholesterol and triglycerides. Several clinical trials, particularly those before the widespread use of statins, demonstrated that niacin therapy could slow the progression of atherosclerosis and reduce the risk of cardiovascular events. For example, the Coronary Drug Project (1975) found that niacin reduced nonfatal myocardial infarction in men with a history of heart attack.

However, more recent large studies (such as AIM-HIGH and HPS2-THRIVE) have shown that adding niacin to statin therapy does not provide additional benefit in reducing major cardiovascular events, and may increase the risk of adverse effects like flushing, liver toxicity, and new-onset diabetes. Guidelines no longer recommend niacin as a first-line therapy for arteriosclerosis or hyperlipidemia, but its use is still considered in specific cases where statins are not tolerated or lipid targets are not achieved. Thus, while there is a scientific basis for its historical use, current evidence suggests limited benefit in the context of modern therapies.

More about Vitamin B3 (unspecified)
More about Arteriosclerosis

Products containing Vitamin B3 (unspecified)

We currently have no products on Caring Sunshine that contain this ingredient.