Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Onion (Allium cepa) has a long history of use in traditional medicine for various cardiovascular conditions, including arteriosclerosis (the thickening and hardening of the arterial walls). More recently, scientific research has begun to explore its potential mechanisms and efficacy in supporting cardiovascular health. Onions are rich in flavonoids, particularly quercetin, and organosulfur compounds, both of which have demonstrated antioxidant, anti-inflammatory, and lipid-lowering properties in laboratory and animal studies. Several experimental studies have shown that onion extracts can reduce blood lipid levels, inhibit platelet aggregation, and improve endothelial function, all of which are beneficial in preventing or slowing the progression of arteriosclerosis.

However, the clinical evidence in humans remains limited and somewhat inconsistent. While small-scale studies and epidemiological data suggest that higher intake of onions and other allium vegetables may be associated with reduced cardiovascular risk, robust clinical trials directly evaluating onion’s effect on arteriosclerosis are lacking. The evidence is therefore rated as moderate but not conclusive (level 2 out of 5). More high-quality, controlled human studies are needed to confirm these findings and to establish effective dosages and safety profiles. In summary, while onion shows promise as a supportive dietary component for cardiovascular health, including arteriosclerosis, its use is best considered complementary rather than primary therapy.

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