Evidence supporting the use of: Flavanols (various)
For the health condition: Arteriosclerosis
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Flavanols, a subclass of flavonoids commonly found in foods such as cocoa, tea, apples, and berries, have been studied for their cardiovascular benefits, including their potential role in supporting or preventing arteriosclerosis (the thickening and hardening of arterial walls). Multiple clinical and epidemiological studies have shown that flavanol-rich foods may improve endothelial function, reduce blood pressure, and decrease oxidative stress and inflammation — all of which are relevant to the pathogenesis of arteriosclerosis.
Cocoa flavanols, in particular, have been the subject of several randomized controlled trials. These studies suggest that regular consumption of flavanol-rich cocoa can improve flow-mediated dilation (a marker of endothelial health) and decrease arterial stiffness. Some meta-analyses support modest reductions in blood pressure and improvements in lipid profiles with flavanol consumption. However, the effects tend to be small, and there is significant heterogeneity in study designs, populations, and dosages.
While there is scientific evidence supporting a potential benefit of flavanols in cardiovascular health, including mechanisms relevant to arteriosclerosis, the quality and consistency of evidence remains moderate. The majority of studies focus on surrogate markers rather than direct clinical outcomes such as reduction in arteriosclerosis progression or cardiovascular events. Thus, while the use of flavanols is scientifically justified, more robust clinical trials are needed to confirm their efficacy in directly treating or preventing arteriosclerosis.
Other ingredients used for Arteriosclerosis
ajoenealpha-linolenic acid (ALA)
anchovies
anthocyanins
apple
beet
berberine
bilberry
black garlic
black tea
blueberry
canola oil
catechins
chokeberry
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
EPA (eicosapentaenoic acid)
fiber blend (proprietary)
fish oil
flavonols
garlic bulb
ginkgo biloba
ginseng
grape
onion
green tea
hawthorn
hesperetin
hesperidin
magnesium
marine lipid
naringin
nattokinase
niacin (vitamin B3)
olive
omega-3 fatty acids
policosanol
psyllium
quercetin
red yeast rice
resveratrol
rutin
sitostanol
soybean
tocotrienols
vitamin C
vitamin D
vitamin E
jiaogulan
polyphenols
cocoa
AMP-activated protein kinase (AMPK)
soy isoflavones
Alcohol
Aronia melanocarpa
Allicin
anthocyanidins
Alliin
anthocyanosides
Chocolate
Danshen
Garlic
Pistachio
walnut
Other health conditions supported by flavanols (various)
Alzheimer's DiseaseArteriosclerosis
Blood Clots (prevention of)
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Circulation (to the brain)
Congestive Heart Failure
Diabetes
Diabetic Retinopathy
Digestion (poor)
Fatigue
Free Radical Damage
Gastritis
Gingivitis
Hypertension
Inflammation
Inflammatory Bowel Disorders
Memory and Brain Function
Osteoporosis
Peripheral Neuropathy
Rheumatoid Arthritis
Skin Care (general)
Stress
Triglycerides (high)
Varicose Veins
Wrinkles