Evidence supporting the use of: Anthocyanosides
For the health condition: Arteriosclerosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Anthocyanosides, a class of flavonoid compounds found in berries such as bilberry, have been studied for their potential cardiovascular benefits, including effects relevant to arteriosclerosis (the thickening and hardening of arterial walls). Scientific interest is based primarily on their antioxidant properties, which can help neutralize free radicals and reduce oxidative stress—a contributor to arterial damage and plaque formation. Additionally, anthocyanosides may improve endothelial function, modulate inflammation, and inhibit the oxidation of low-density lipoprotein (LDL) cholesterol, which is a key factor in the development of arteriosclerosis.

Despite promising mechanisms observed in vitro and in animal studies, human clinical evidence remains limited and of variable quality. Some small clinical trials and observational studies have suggested that diets rich in anthocyanin-containing foods may be associated with improved cardiovascular outcomes and vascular function, but direct evidence supporting anthocyanosides as a treatment for arteriosclerosis is lacking. Systematic reviews (e.g., Wallace et al., 2016; Cassidy et al., 2013) conclude that while anthocyanins may have a modest positive effect on cardiovascular risk factors, robust randomized controlled trials focused specifically on arteriosclerosis are insufficient. Thus, while there is a scientific rationale and some preliminary evidence, the clinical efficacy for arteriosclerosis is not well established.

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Products containing anthocyanosides

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