Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E (mixed tocopherols and tocotrienols) and Arterial Health

Vitamin E, a fat-soluble antioxidant encompassing tocopherols and tocotrienols, has been studied for its potential role in supporting cardiovascular and arterial health. The scientific rationale is largely based on its antioxidant properties, which may help protect blood vessels from oxidative stress, a contributor to atherosclerosis (the buildup of plaque in arteries).

Several observational studies have associated higher dietary intake of vitamin E with a reduced risk of coronary artery disease. Some early clinical trials suggested that vitamin E supplementation might help reduce the progression of atherosclerosis by inhibiting the oxidation of low-density lipoprotein (LDL) cholesterol, a key step in plaque formation. Tocotrienols, a less common form of vitamin E, have shown additional potential in preclinical studies, such as reducing cholesterol synthesis and inflammation in blood vessels.

However, large randomized controlled trials (RCTs) in humans have yielded mixed or negative results. Meta-analyses and reviews, including those by the American Heart Association, generally conclude that vitamin E supplements do not significantly lower the risk of major cardiovascular events or improve arterial health in the general population. Some studies have even suggested potential harm at high doses. Thus, while there is scientific rationale and some early supportive evidence, robust clinical validation is lacking, and vitamin E supplementation is not broadly recommended for arterial support.

More about Vitamin E (mixied tocopherols and tocotrienols)
More about Arteries

Other ingredients that support Arteries

Other body systems supported by Vitamin E (mixied tocopherols and tocotrienols)

Products containing Vitamin E (mixied tocopherols and tocotrienols)