Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Bishop's Weed (Ammi visnaga), also known as Khella, has a long history of traditional use, especially in Mediterranean and Middle Eastern herbal medicine. Historically, it has been used to address cardiovascular concerns, primarily due to its vasodilatory properties. The active constituents, notably khellin and visnagin, are believed to relax smooth muscle tissues, which may help to dilate blood vessels and support arterial health. However, most of the evidence supporting its use for the arteries and circulation comes from traditional medicine rather than rigorous modern scientific studies.

Some pharmacological studies have indicated that khellin can cause relaxation of coronary arteries, which is why khella extracts were investigated in the early to mid-20th century for angina pectoris and asthma. Nevertheless, clinical evidence remains limited, and Bishop's Weed has largely been replaced by more effective and safer modern drugs for these conditions. There are few controlled clinical trials, and the available data is not robust enough to firmly support its widespread use for arterial health. Thus, while there is a basis in traditional use and some pharmacological rationale, scientific validation is weak, justifying a moderate-low evidence rating.

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