Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bergamot (Citrus bergamia) is a citrus fruit whose extract, particularly in the form of bergamot polyphenolic fraction (BPF), has been studied for its potential cardiovascular benefits, including support for arterial health. Scientific research over the past decade has shown that bergamot extract can help lower total cholesterol, LDL cholesterol, and triglyceride levels, while raising HDL cholesterol. Several clinical trials and observational studies have demonstrated its efficacy in improving lipid profiles in patients with hyperlipidemia, a known risk factor for atherosclerosis and arterial disease.

The mechanisms attributed to bergamot’s effects include inhibition of HMG-CoA reductase (the same enzyme targeted by statin drugs), antioxidant activity that reduces oxidative stress on artery walls, and anti-inflammatory properties. A 2013 study published in “Fitoterapia” and subsequent research have reported improvements in endothelial function—an important factor in arterial health—after supplementation with bergamot-derived polyphenols. However, while these results are promising, the number of high-quality, large-scale randomized controlled trials remains limited. Most data come from small to moderate-sized studies or preclinical research.

In summary, there is moderate scientific support for using bergamot to support the arteries, particularly in the context of improving cholesterol profiles and reducing cardiovascular risk factors. Its use is not purely traditional; rather, there is a growing body of scientific evidence, though more robust clinical trials are needed to confirm its efficacy and safety for long-term arterial health.

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