Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the health condition: Arrhythmia

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Coenzyme Q10 (CoQ10) has been investigated for its potential role in supporting or treating arrhythmias, but the current scientific evidence is limited and not robust. CoQ10 is a fat-soluble antioxidant that plays a crucial role in mitochondrial energy production, particularly in tissues with high energy demands such as the heart. Some small clinical studies and case reports suggest that CoQ10 supplementation may help reduce the frequency or severity of certain arrhythmias, especially in patients with underlying heart conditions like heart failure or ischemic heart disease. The proposed mechanism is that CoQ10 improves myocardial energy production and reduces oxidative stress, potentially stabilizing cardiac electrical activity. However, the quality and size of the studies conducted to date are generally low, often lacking randomization, blinding, or adequate sample sizes. Meta-analyses and systematic reviews have found insufficient evidence to support routine use of CoQ10 for arrhythmia management, though it may have modest benefit as an adjunct in select populations. There is no strong guideline recommendation for CoQ10 as a primary treatment for arrhythmias. In summary, while there is some scientific rationale and preliminary evidence supporting its use, the overall strength of evidence is low, and CoQ10 should not replace standard antiarrhythmic therapies.

More about coenzyme Q10 (CoQ10)
More about Arrhythmia