Evidence supporting the use of: Thylakoid
For the health condition: Appetite (excessive)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Thylakoid—membrane-bound compartments found in the chloroplasts of green plants—have been researched for their potential effects on appetite regulation. Scientific studies have shown that thylakoid extracts, often derived from spinach, can help decrease appetite and support weight management. The proposed mechanism involves thylakoids delaying fat digestion in the gastrointestinal tract, which, in turn, increases the release of satiety hormones such as cholecystokinin (CCK) and glucagon-like peptide-1 (GLP-1). This effect has been demonstrated in several human clinical trials: for example, a randomized controlled trial published in Appetite (2014) reported that participants who consumed thylakoid-enriched drinks experienced reduced hunger and fewer cravings compared to controls. Other studies have replicated these findings, showing that thylakoid supplementation leads to reduced caloric intake and promoted feelings of fullness. While the overall body of evidence is not yet large, and most studies have been of relatively short duration, the findings are consistent and suggest a genuine effect on appetite suppression. Thus, the use of thylakoid for managing excessive appetite is supported by early scientific validation, but further long-term studies are needed to determine efficacy and safety more comprehensively.

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