Codonopsis (often referred to as Codonopsis pilosula, or "dang shen") is a well-known herb in Traditional Chinese Medicine (TCM). Historically, it has been used as a tonic to strengthen the "qi" (vital energy), especially in individuals who are weak, fatigued, or who have poor appetite due to deficiency syndromes. The traditional application for deficient appetite is based on its reputed ability to tonify the spleen and stomach, organs that are considered central to digestion and nutrient absorption in TCM theory. Practitioners often prescribe Codonopsis for patients who display symptoms such as lack of appetite, fatigue, and digestive weakness, frequently as a gentler alternative to ginseng.

While there is a strong tradition of use, scientific evidence specifically validating Codonopsis for appetite stimulation in humans is limited. Some animal studies and in vitro research suggest immunomodulatory, adaptogenic, and digestive-supporting effects, but robust clinical trials in humans are lacking. Nonetheless, the traditional context—supported by centuries of empirical use in East Asian medicine—provides moderate evidence for its role in supporting appetite, particularly when the loss of appetite is related to underlying deficiency or weakness as defined in TCM.

In summary, Codonopsis's use for deficient appetite is primarily justified by traditional practice rather than rigorous scientific validation.