Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Calories, representing the energy content derived from food, have robust scientific validation for their role in supporting or treating deficient appetite (anorexia or undernutrition). The consumption of adequate calories is fundamental for maintaining body weight, supporting metabolic functions, and preventing malnutrition. In cases of appetite deficiency—due to illness, aging, or medical treatments—provision of sufficient calories (via oral, enteral, or parenteral nutrition) is a cornerstone of medical nutrition therapy. Clinical guidelines from organizations such as the American Society for Parenteral and Enteral Nutrition (ASPEN) and the European Society for Clinical Nutrition and Metabolism (ESPEN) emphasize the necessity of calorie provision to restore energy balance and promote recovery in patients with poor appetite. Numerous studies demonstrate that calorie supplementation in individuals with insufficient intake leads to improvements in weight, muscle mass, immune function, and overall clinical outcomes. While calories themselves do not directly stimulate appetite, their administration is essential to reverse or prevent the negative consequences of appetite deficiency. Thus, the use of calories to treat or support deficient appetite is both scientifically validated and universally accepted in medical practice.

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