Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Bupleurum is primarily used in traditional Chinese medicine (TCM) and other East Asian medical systems for its supposed effects on the liver, qi regulation, and as part of multi-herb formulas. In TCM, Bupleurum is often included in prescriptions designed to address what is described as "deficient appetite," which is sometimes attributed to stagnation of liver qi or digestive weakness. The classic herbal formula Xiao Yao San ("Rambling Powder"), which contains Bupleurum as a chief ingredient, is traditionally used to harmonize the liver and spleen, and is prescribed for symptoms including poor appetite, fatigue, and digestive disturbances. However, these uses are rooted in traditional concepts and not in biomedical research.

There is little direct scientific evidence that Bupleurum itself improves appetite in clinical or preclinical studies. Modern research has largely focused on Bupleurum's anti-inflammatory, hepatoprotective, and immunomodulatory properties rather than its effects on appetite. Thus, while Bupleurum is historically and traditionally used to support deficient appetite, this use is not validated by rigorous scientific studies. The evidence supporting its use for appetite loss is primarily traditional, based on centuries of empirical observation in herbal medicine systems, rather than on modern clinical trials.

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