Evidence supporting the use of: Curcumin
For the health condition: Anxiety Disorders
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Curcumin, the main active compound in turmeric (Curcuma longa), has gained scientific interest for its potential role in supporting or treating anxiety disorders. While curcumin has a long history of use in traditional medicine for various ailments, its use specifically for anxiety is more recent and primarily based on emerging scientific research rather than traditional use for this particular condition.
Preclinical studies suggest that curcumin exerts anxiolytic (anxiety-reducing) effects, possibly by modulating neurotransmitter levels (such as serotonin and dopamine), reducing inflammation, and acting as an antioxidant. Animal studies have shown reduced anxiety-like behaviors following curcumin administration. A few small-scale, randomized controlled trials in humans have investigated curcumin supplementation in people with major depressive disorder, some of whom also had anxiety symptoms. These studies reported reductions in anxiety scores compared to placebo, but the sample sizes were small and the effect sizes modest.
The evidence is not yet robust, with most clinical studies limited by small cohorts, short duration, and variability in curcumin formulations and dosages. There is a need for larger, well-controlled clinical trials to establish efficacy and optimal dosing. Nonetheless, current findings provide preliminary support for curcumin as a potential adjunctive therapy for anxiety, justifying a moderate evidence rating. It should not replace standard treatments but may be considered as a complementary option under medical supervision.
Other ingredients used for Anxiety Disorders
5-Hydroxytryptophan (5-HTP)amino acids
ashwagandha
waterhyssop
beta caryophyllene
bifidobacterium infantis
bifidobacterium longum
cannabis sativa oil
chamomile
citrus oil
curcumin
ginkgo biloba
ginseng
gotu kola
green tea
hemp oil
inositol
kava root
l-glycine
l-taurine
l-theanine
l-tryptophan
lactium casein decapeptide
lactobacillus casei
lactobacillus paracasei
lactobacillus rhamnosus
lavender
lion's mane
lithium orotate
magnesium
magnolia
matcha
melatonin
motherwort
muira puama
n-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
phosphatidylserine
phytocannabinoids
polygala root
prebiotic blend (proprietary)
pregnenolone
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
rhodiola
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sceletium
skullcap
valerian root
velvet bean
vitamin B
vitamin B12
vitamin B6
zinc
catnip
shen-chu
St. John's Wort
herbal blend (proprietary)
cocoa
7,8-Dihydroxyflavone
Apigenin
Albizia
Aconite
Baikal Skullcap
Bifidobacterium adolescentis
Bacopin
Brahmi
Bacopa
bacoside
Clary sage
Cymbopogon Martini
Centella asiatica
Capitate Valerian
Cowslip
Cannabidiol
Convolvulus prostratus
Convolvulus Pluricaulis
Essential Oil Blend
Spikenard
Sandalwood
Vervain
yohimbine
Other health conditions supported by curcumin
AbscessesAcne
Adenitis
Aging (prevention)
Allergies (respiratory)
Alzheimer's Disease
Anal Fistula or Fissure
Angina
Antibiotics (alternatives to)
Anxiety
Anxiety Disorders
Arteriosclerosis
Arthritis
Asthma
Athletic and Exercise Aids
Autism
Autoimmune Disorders
Backache
Belching
Benign Prostate Hyperplasia
Bites and Stings
Bleeding (external)
Blood Clots (prevention of)
Body Building
Boils
Breast Lumps
Broken Bones
Bronchitis
Bruises (healing)
Bruises (prevention)
Burns and Scalds
Bursitis
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Canker Sores
Carbuncles
Cardiovascular Disease
Cartilage Damage
Celiac Disease
Cervical Dysplasia
Chemical Poisoning
Chemotherapy (reducing side effects)
Cholesterol (high)
Chronic Obstructive Pulmonary Disorder
Circulation (poor)
Cirrhosis of the Liver
Colitis
Crohn's Disease
Depression
Diabetes
Dyspepsia
Eczema
Endometriosis
Fatty Liver Disease
Fibromyalgia Syndrome
Fibrosis
Indigestion
Infection (bacterial)
Infection (viral)
Inflammation
Inflammatory Bowel Disorders
Irritable Bowel Syndrome
Liver Detoxification
Memory and Brain Function
Metabolic Syndrome
Migraine
Osteoporosis
Pain (general remedies for)
Pancreatitis
Pap Smear (abnormal)
Parkinson's Disease
Peripheral Neuropathy
Psoriasis
Rheumatoid Arthritis
Spinal Disks
Stress
Ulcers
Wounds and Sores