Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Ashwagandha (Withania somnifera) is a traditional herb in Ayurvedic medicine, long used for its adaptogenic properties that help the body manage stress. In recent years, its use for anxiety disorders has gained scientific attention. Several randomized controlled trials (RCTs) have investigated ashwagandha’s efficacy in reducing symptoms of anxiety. A 2019 meta-analysis of five RCTs found that ashwagandha supplementation was associated with significant reductions in anxiety compared to placebo, though the included studies were small and varied in quality. The proposed mechanisms of action include modulation of the hypothalamic-pituitary-adrenal (HPA) axis and reduction of cortisol levels, as well as potential effects on GABAergic signaling, which is relevant to anxiety regulation.

Despite these promising results, the overall quality of evidence is moderate. Many studies have small sample sizes, short durations, or potential conflicts of interest, such as funding by supplement manufacturers. There is a need for larger, independent trials with rigorous methodology to confirm efficacy and safety for clinical use in anxiety disorders. Nevertheless, current scientific evidence suggests ashwagandha may offer mild to moderate benefit for anxiety, particularly for people with mild to moderate symptoms or those seeking complementary approaches. Anyone considering ashwagandha for anxiety should consult a healthcare provider, especially if already on medication or with underlying health conditions.

More about ashwagandha
More about Anxiety Disorders

Other ingredients used for Anxiety Disorders

Other health conditions supported by ashwagandha

Products containing ashwagandha

Nature's Sunshine 5-HTP Power
Nature's Sunshine AdaptaMax
Nature's Sunshine Joint Health (Ayurvedic)
Nature's Sunshine Glandular System
Nature's Sunshine Nervous System (30 Day Program)
Nature's Sunshine Power Meal
Nature's Sunshine Power Meal
Nature's Sunshine Ultrabiome DTX