Evidence supporting the use of: Inositol
For the health condition: Anxiety

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Inositol, particularly the myo-inositol form, has been investigated for its role in supporting and treating anxiety, especially within the context of panic disorder and obsessive-compulsive disorder (OCD). Several clinical studies have explored its efficacy. For example, a double-blind, placebo-controlled study published in the American Journal of Psychiatry (1995) found that patients with panic disorder who received inositol (18g per day) experienced significantly fewer panic attacks compared to placebo. Additional research, including a 2001 study in European Neuropsychopharmacology, also suggested potential benefit for those with panic disorder and OCD. Myo-inositol appears to act on neurotransmitter pathways, particularly influencing serotonin signaling, which is implicated in anxiety regulation.

However, the body of evidence remains relatively limited, with most studies being small and of short duration. There is a lack of large-scale, long-term clinical trials, and the optimal dosing and safety profile are not fully established outside of research settings. Nonetheless, the existing data provide moderate scientific validation for the use of inositol in certain anxiety-related conditions, particularly panic disorder, justifying a rating of 3 out of 5. Inositol is generally well-tolerated, with mild gastrointestinal side effects being the most commonly reported issue. More research is needed to clarify its role in generalized anxiety disorder and other anxiety-related conditions.

More about inositol
More about Anxiety

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7,8-Dihydroxyflavone
Aconite
Agarwood
Agastache
Agmatine
Agrimony
Albizia
Alpha lactalbumin
alpha-pinene
alpha-terpineol
amino acids
Amor seco
anamu
Anemone
aniracetam
anise
apigenin
Ardisia
ash
ashwagandha
Asteraceae
Bacopa
Bacopin
bacoside
bacteria
baicalein
baicalin
Baikal Skullcap
balsam
basil
bayleaf
bee products
benegut perilla (proprietary)
bergamot
beta caryophyllene
betony
Bifidobacteria
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium bifidum
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
black cumin
black seed
blackboard tree
Bombax
borneol
brahmi
Bupleurum
bupleurum falcatum
calamus
Calea zacatechichi
California poppy
Camellia sinensis
cannabidiol
cannabigerol
Cannabis sativa oil
Canscora
capillary artemisia
Capitate Valerian
cardamom
caryophyllene
catnip
catuaba
Centella asiatica
Centella triterpenes
chamomile
Chinese raisintree
Chinese salvia root
chrysanthemum
Cinnamomum
citron
Clary sage
Clerodendrum indicum
Clostridium butyricum
clove
cocoa
Convolvulus pluricaulis
Convolvulus prostratus
cordyceps
cowslip
Curcuma
curcumin
Cymbopogon martini
damiana
DHA (docosahexaenoic acid)
dodeca-2E, 4E-dienoic acid isobutylamide
dragonhead
epigallocatechin gallate (EGCG)
Erythrina
essential oil blend
eugenol
fatty acids
fennel
Ficus religiosa
fragrant rosewood
fungus
ganoderma
gardenia
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gastrodia
gastrodin
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geranium
ginkgo biloba
ginseng
Ginsenosides
Glycine
gotu kola
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green tea
Griffonia simplicifolia
guayusa
heal-all
hemp
hemp oil
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herbal blend (proprietary)
hericium mushroom
honeybush
Honokiol
hops
hyperforin
Hypericum
Hyperoside
Ilex
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Indian tinospora
indigo leaves
inositol
iridoids
isoliquiritigenin
jasmine
Jatamansi
jujube
jujubosides
kanna
kava
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Kefir
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lactiplantibacillus plantarum
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Lactobacillus johnsonii
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Lactucarium
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lavender
lemon balm
lemongrass
ligustilides
limonene
linalool
linden
lingzhi
lion's mane
lithium orotate
Litsea
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lotus
lupulinum
Lycopodium
maca
magnesium
magnolia
magnolol
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Motherwort
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Muira puama
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Myrcene
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Nardostachys
Nigella seed
Nutmeg
Nymphaea caerulea
Nymphaea nouchali
omega-3 fatty acids
oolong tea
oriental arborvitae
Oroxylum indicum
Osmanthus
Oxindole alkaloids
paeoniflorin
passionflower
Passionfruit
Patchouli oil
peony
Petiveria
Phellodendron
phellodendron amurense
Phenylpropanoids
phosphatidylserine
phytocannabinoids
Plectranthus amboinicus
Polygala
polygala root
poppy
prebiotic blend (proprietary)
pregnenolone
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probiotics
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relora® (proprietary)
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Terpenoids
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Uncaria
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