Albizia species, particularly Albizia julibrissin (commonly known as the silk tree or mimosa tree), have a long history of use in traditional Chinese medicine (TCM) for mood disorders, including anxiety and depression. In TCM, Albizia flowers ("He Huan Hua") and bark ("He Huan Pi") are traditionally prescribed to "calm the spirit," relieve emotional constraint, and treat symptoms such as irritability, insomnia, and anxiety. The use is documented in classical herbal texts, and Albizia preparations are still commonly found in modern Chinese herbal formulas targeting mental wellness.

Scientific validation for Albizia's anxiolytic effects is limited but growing. A few animal studies suggest that extracts from Albizia julibrissin may have sedative and anxiolytic properties, possibly due to flavonoids, saponins, and other phytochemicals. However, robust clinical trials in humans are lacking, and most of the supporting evidence remains preclinical or anecdotal. There is also variability in the species and plant parts used, and standardization of doses is not well established.

In summary, the use of Albizia for anxiety is primarily justified by traditional and historical use rather than strong scientific validation. While preliminary data are promising, more rigorous human studies are needed to substantiate its efficacy and safety for anxiety treatment.