Evidence supporting the use of: Lactobacillus casei
For the health condition: Antibiotics (side effects of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactobacillus casei is a probiotic bacterium commonly included in supplements designed to support gut health, especially during or after antibiotic treatment. Antibiotics often disrupt the natural balance of the gut microbiota, leading to side effects such as antibiotic-associated diarrhea (AAD). There is a growing body of scientific evidence suggesting that certain probiotic strains, including Lactobacillus casei, can help restore microbial balance and reduce the risk and severity of AAD. Several randomized controlled trials and meta-analyses have demonstrated that probiotics, and specifically some strains of Lactobacillus, can decrease the incidence of diarrhea in patients undergoing antibiotic therapy. For example, a 2010 meta-analysis in the journal International Journal of Antimicrobial Agents found that probiotics reduced the risk of AAD by nearly half, with L. casei among the beneficial strains studied. However, the effectiveness can vary depending on the strain, dosage, and patient population, and not all studies have shown consistent results. Overall, the evidence supporting the use of Lactobacillus casei for mitigating antibiotic side effects is moderate, justifying a rating of 3 out of 5. Nevertheless, probiotic use is generally considered safe for most people, though caution is advised in immunocompromised individuals. As always, it is best to consult a healthcare provider before starting any new supplement during antibiotic therapy.

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