Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bifidobacterium animalis is a probiotic bacterium that has been studied for its potential to mitigate the side effects of antibiotics, particularly antibiotic-associated diarrhea (AAD). Antibiotics can disrupt the normal gut microbiota, leading to gastrointestinal side effects such as diarrhea. Several randomized controlled trials and systematic reviews have examined the efficacy of Bifidobacterium species, including B. animalis (notably strains like B. animalis subsp. lactis), in reducing the incidence and severity of AAD.

A 2015 meta-analysis published in the Journal of Pediatric Gastroenterology and Nutrition found that certain probiotics, including B. animalis subsp. lactis, can significantly reduce the risk of AAD in children. Similar findings have been reported in adult populations. The mechanism is believed to involve restoration of the balance of intestinal microbiota and enhancement of gut barrier function.

However, while the overall evidence supports a beneficial effect, the quality of studies varies, and some trials are limited by small sample sizes or the use of mixed probiotic formulations, making it difficult to isolate the specific effect of B. animalis. Nonetheless, products containing B. animalis are commonly recommended and used for supporting gut health during or after antibiotic therapy. The scientific consensus is moderately supportive, but further large, high-quality studies would help clarify its effectiveness and optimal use.

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