Evidence supporting the use of: EGCG
For the health condition: Antibiotics (alternatives to)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Epigallocatechin gallate (EGCG), a major catechin found in green tea, has been researched for its antimicrobial properties and its potential role as an adjunct or alternative to antibiotics. Several in vitro studies demonstrate that EGCG can inhibit the growth of a range of bacteria, including antibiotic-resistant strains such as Staphylococcus aureus (including MRSA), Escherichia coli, and Pseudomonas aeruginosa. EGCG appears to disrupt bacterial cell membranes, inhibit enzyme activity, and interfere with the formation of biofilms, which are protective layers that make bacteria more resistant to antibiotics.

Moreover, EGCG has been shown in some preclinical research to synergize with certain antibiotics, enhancing their effectiveness and reducing the required dosage. For example, studies published in journals such as Frontiers in Microbiology (2019) and International Journal of Antimicrobial Agents (2017) report that EGCG can restore the activity of β-lactam antibiotics against resistant bacteria in laboratory settings. However, there is a lack of robust clinical trials in humans, and its bioavailability after oral consumption is limited.

In summary, while there is promising laboratory evidence for EGCG supporting or enhancing antibiotic therapy, especially against resistant bacteria, clinical validation is incomplete. Thus, its use in this context is based on scientific research at the preclinical level, but not yet supported by strong clinical evidence, meriting a moderate evidence rating.

More about EGCG
More about Antibiotics (alternatives to)

Other ingredients used for Antibiotics (alternatives to)

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ajoene
astragalus
bacillus clausii
bacillus subtilis
berberine
black cumin
black walnut
caprylic acid
caterpillar mushroom
clove
colostrum
Coptis chinensis
turmeric
curcumin
epigallocatechin gallate (EGCG)
garlic bulb
ginger
goldenseal
gooseberry
green tea
horseradish
Indian tinospora
honeysuckle
lactobacillus bulgaricus
lactobacillus fermentum
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
lactoferrin
lactoperoxidase
lauric acid
lentinula edodes mycelia
LH01-myoviridae
mastic gum
monolaurin
oregano
oregon grape
oyster mushroom
phenolic acids
plantain
butyric acid
rhizome
sage
shiitake mushroom
thyme
vitamin C
wasabia japonica
zinc
yellow root
papaya
neem tree
clerodendrum indicum
pistacia integerrima gall
paederia foetida
pau d'arco
myrrh
morinda
oriental arborvitae
melaleuca alternifolia
algae
geranium
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3-Phenyllactic Acid
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Azelaic acid
Allicin
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Alchornea
Aucubin
Andrographolide
Andrographis
Alsonia scholaris
Asteracea
Allyl Sulfide
Acemannan
Algal protein
Alliin
Alantolactone
Bee Propolis
Bacillus indicus
Baphicacanthus cusia
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Betulinic acid
Butea monosperma
Brazillian peppertree
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Basidiomycota
Bacillus licheniformis
Brevibacillus laterosporus
Bee products
Bombax
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benzyl isothiocyanate
Baicalin
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Capric Acid
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coconut oil
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Cinnamic Acid
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Dichrostachys glomerata
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Eugenol
Flavonoids
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Products containing EGCG

We currently have no products on Caring Sunshine that contain this ingredient.